Sepsis, lactate, and oxygen supply dependence.
نویسنده
چکیده
www.chestpubs.org 2 . Bouros D , Wells AU , Nicholson AG , et al . Histopathologic subsets of fi brosing alveolitis in patients with systemic sclerosis and their relationship to outcome . Am J Respir Crit Care Med . 2002 ; 165 ( 12 ): 1581 1586 . 3 . Betteridge ZE , Gunawardena H , McHugh NJ . Novel autoantibodies and clinical phenotypes in adult and juvenile myositis . Arthritis Res Ther . 2011 ; 13 ( 2 ): 209 . 4 . Gunawardena H , Betteridge ZE , McHugh NJ . Newly identifi ed autoantibodies: relationship to idiopathic infl ammatory myopathy subsets and pathogenesis . Curr Opin Rheumatol . 2008 ; 20 ( 6 ): 675 680 .
منابع مشابه
Lack of oxygen supply dependency in patients with severe sepsis. A study of oxygen delivery increased by military antishock trouser and dobutamine.
BACKGROUND During severe sepsis, the existence of a pathologic oxygen supply dependency remains controversial. STUDY OBJECTIVE To evaluate the relationship between oxygen delivery (DO2) and oxygen consumption (VO2) during severe sepsis and to compare, in this respect, survivors and nonsurvivors and patients with normal or increased concentration of plasma lactate. STUDY DESIGN Cohort analyt...
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Background: The Surviving Sepsis Campaign international consensus guidelines recommend early resuscitation to optimize oxygen delivery. Although the best measure of oxygen delivery is debated, the published protocol utilized central venous oxygen saturation (ScvO2) of >70%. Serum lactate has been shown to prognosticate outcome, with higher levels being associated with worse morbidity and mortal...
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One of the main aspects of the initial phase of the septic inflammatory response to a bacterial infection is abnormal microvascular perfusion, including decreased functional capillary density (FCD) and increased blood flow heterogeneity. On the other hand, one of the most important phenomena observed in the later stages of sepsis is an increased dependence of tissue O 2 utilization on the conve...
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ورودعنوان ژورنال:
- Chest
دوره 141 5 شماره
صفحات -
تاریخ انتشار 2012